Sikeston has many churches and denominations available for your worship needs. It is our goal that every visitor feel included as a part of the family of God in Sikeston, Missouri. Below is a directory of churches in Sikeston.
| Bethel Missionary Baptist 128 5th St. 573-471-3750 |
Cape First of Sikeston 416 Greer (573) 471-4948 |
Christian Tabernacle United Pentecostal Hwy. 60E (573) 471-0677 |
Church of Christ Shady Acres 1440 Ables Rd. (573) 471-5186 |
| Church of Jesus Christ of Latter Day Saints 827 Euclid (573)471-0519 |
Church of the Living Word 533 S. Frisco |
Church on the Rock Hwy. 60 West (573) 472-4491 |
Community Baptist 101 East Gladys (573) 471-3368 |
| Concordia Lutheran (LCMS) Park & Wakefield (573)471-5842 |
Cornerstone Baptist 127 W. Trotter St Sikeston, MO (573)471-5054 |
Crossroads Community 303 Rogers Miner, MO |
Emmanuel Missionary Baptist 2001 Ables Road (573) 471-7687 |
| Fellowship Baptist 1801 Ables Road (573) 471-2778 |
First Assembly of God 306 S. Kingshighway (573) 471-4649 |
First Baptist Church 1101 N. Main (573) 471-4122 |
First Christian Church 1006 N. Main (573) 471-3613 |
| First Church of Nazarene 1521 N. Main (573) 471-4403 |
First United Methodist 1307 N. Main St. (573) 471-3283 |
First United Pentecostal 38 Matthews Ave. (573) 471-5334 |
Glory of God Church of God in Christ 219 Edmondson St. (573) 41-4200 |
| Green Memorial Church of God in Christ 113 Clayton Ave. (573) 471-5217 |
Hunter Memorial First Presbyterian 723 Allen Blvd. (573) 471-3267 |
Life Church S. Main & Stalcup (573) 471-6020 |
Living Grace Fellowship 303 Rogers (573) 472-9446 |
| Living Waters 328 W. North St. (573) 472-4713 |
Miner Baptist 416 State Hwy H (573) 471-1331 |
Murray Lane Baptist 807 W. Murray Lane (573) 471-0034 |
New Beginnings Fellowship 720 David Lane (573) 471-0034 |
| New Harvest Outreach 303 Rogers (573) 667-9912 |
New Hope Baptist 204 Rogers (573) 471-2144 |
New Deliverance Praise and Worship Center 1217 W. Malone (573) 471-1533 |
North Acres General Baptist 202 Kennedy Dr. (573) 471-3419 |
| Orthodox Anglican Currently meeting at 102 Ridge Drive (573) 472-1495 |
Potter's House Ministries 109 Smith Street (573) 471-3620 |
River of Life Worship Center Hwy 61 N./Calvary Drive (573) 471-7590 |
Sandywood Baptist 503 Sandywood Lane (573) 472-7899 |
| Smith Ave. Church of God 420 Smith Street (573) 471-0209 |
Smith Chapel United Methodist 201 Young Street (573) 472-1647 |
St. Francis Xavier Catholic Church 106 N. Stoddard St. (573) 471-2447 |
St. Johns Missionary Baptist 232 Westgate (573) 471-1855 |
| St. Paul's Episcopal 1010 N. Main (573) 471-2680 |
Tanner Street Church of God 619 Tanner St. (573) 471-5469 |
Temple of Faith Baptist 309 Smith St. |
The Country Church 711 Davis Blvd. (573) 380-9109 |
| Trinity Baptist Hwy. 61 North (573) 471-9435 |
Trinity Gospel 901 Davis (573)471-1735 |
The Inspired Word of Church of Jesus Christ of the Apostolic Faith 301 William St. (573) 481-9490 |
Wesley United Methodist Corner of Pine & Ables (573) 471-0384 |
| West End Missionary Baptist 1004 Maude (573) 471-7157 |